At the cellular level, the phase 1 CYPs, FMOs, and EHs, and some phase 2 conjugating enzymes, notably the UGTs, are all located in the endoplasmic reticulum of the cell (Figure 62)
A central regulatory role in this pathway is played by the BCL-2 family of proteins, which consists of anti-apoptotic members (e.g., BCL-2, BCL-XL, MCL-1), pro-apoptotic multidomain effector proteins (BAX and BAK), and pro-apoptotic BH3-only proteins (e.g., PUMA, NOXA, BIM, BID)
PMID 40160308
Provides immune system support: It helps regulate white blood cell activity, boost immune function, and protect against illness
PLoS ONE 9 , e86300 (2014)
Yes, glutathione injections are often combined with vitamin C under medical supervision, as vitamin C helps regenerate glutathione and enhance its antioxidant effects